Relieve Knee Pain Without Surgery

Do you suffer from chronic knee pain? Whether it’s caused by osteoarthritis or degenerative joint disease, knee pain can disrupt your life. At San Francisco Vein and Vascular Institute (SFVVI), we offer Genicular Artery Embolization (GAE) – a minimally invasive procedure designed to provide significant and lasting relief from knee pain associated with osteoarthritis and degenerative joint disease. Performed by skilled vascular surgeons in a state-of-the-art ambulatory surgery center, this advanced treatment is delivered in a comfortable, patient-focused environment.

What is Genicular Artery Embolization?

Genicular Artery Embolization (GAE) is a minimally invasive, non-surgical procedure designed to relieve chronic knee pain caused by osteoarthritis. This procedure reduces inflammation by decreasing blood flow to the knee’s synovium (the tissue lining the joint), helping to alleviate pain and improve mobility for those suffering from moderate to severe knee osteoarthritis.

GAE is an outpatient procedure, meaning patients return home the same day and can resume normal activities within days. It is an excellent option for individuals who have not found relief with medications, physical therapy, or injections—and who want to avoid or delay knee replacement surgery.

Key Benefits of GAE:

  • Minimally Invasive: No incisions or general anesthesia required.

  • Outpatient Procedure: Patients return home the same day.

  • Quick Recovery: Most individuals resume normal activities shortly after the procedure.

  • Proven Results: Clinical studies show significant pain reduction, with many patients experiencing relief lasting up to two years.

  • Reduces Dependency on Pain Medications: Patients often need fewer medications after the procedure.

  • Non-Surgical Alternative to Knee Replacement: Ideal for those seeking pain relief without undergoing invasive surgery.

Am I a Candidate for GAE?

GAE is recommended for individuals who:

  • Are between the ages of 40-80

  • Experience chronic knee pain that affects daily activities

  • Have tried conservative treatments (physical therapy, medications, or steroid injections) without success

  • Prefer to avoid or delay total knee replacement surgery

If you meet these criteria, GAE might be a great option for you. To help determine your eligibility, take our quick WOMAC Survey. If your score is above 25, there’s a strong chance you may be a good candidate for GAE.

A high score doesn’t guarantee candidacy, but it’s a great first step! To confirm whether GAE is right for you, schedule a consultation with our physician to discuss your symptoms and treatment options.


How Does the Procedure Work?

GAE is performed in a state-of-the-art surgical facility using advanced imaging technology for maximum precision and effectiveness.

Step-by-Step Overview:

  1. Preparation:

    • The procedure is performed under local anesthesia with mild sedation for comfort. A small catheter is inserted into the femoral artery through a tiny puncture in the groin or upper thigh.

  2. Targeting the Pain-Related Arteries:

    • Using X-ray imaging (fluoroscopy), the doctor carefully guides the catheter to the genicular arteries—tiny blood vessels supplying the inflamed synovium in the knee.

  3. Embolization Process:

    • Once the arteries responsible for excessive blood flow to the knee are identified, microscopic particles are injected to block these arteries, reducing inflammation and pain.

  4. Completion & Recovery:

    • The catheter is removed, and the puncture site is covered with a small bandage—no stitches required.

    • Most patients walk out of the facility within a few hours and return to normal activities within days.

What to Expect After GAE:

Patients often experience pain relief within days to weeks, with continued improvement over several months. Clinical studies show that many patients experience significant pain reduction lasting up to two years.

  • No hospital stay is required.

  • Most individuals return to work and daily activities within a few days.

  • Follow-up appointments help track your progress and ensure optimal results.

Since GAE does not alter the knee’s structure, patients who eventually decide to have knee replacement surgery in the future will still be eligible.

Why Choose SFVVI?

At San Francisco Vein & Vascular Institute (SFVVI), we provide cutting-edge vascular care in a state-of-the-art, Medicare-approved ambulatory surgical center (ASC). Our facility is designed to ensure the highest level of patient safety, comfort, and efficiency while delivering minimally invasive treatments with exceptional outcomes.

  • Expertise: Our team is led by Dr. Daniel Nathanson, Chief of Vascular Surgery at California Pacific Medical Center (CPMC), ensuring your care is provided by one of the most experienced vascular surgeons in the field.

  • Medicare-Approved ASC – Our ambulatory surgical center meets strict national healthcare standards, offering hospital-level care in a convenient, outpatient setting.

  • State-of-the-Art Facility – We utilize the latest imaging technology and minimally invasive techniques to ensure precise, effective, and safe treatments.

  • Comprehensive, Patient-Centered Care – From initial consultation to post-procedure follow-up, our team prioritizes personalized treatment plans tailored to your specific needs.

  • Faster Recovery, Minimal Downtime – As an outpatient procedure, GAE allows patients to return home the same day and recover quickly, without the need for hospitalization.

Schedule a Consultation:

If you suffer from knee osteoarthritis and want to explore a minimally invasive alternative to surgery, contact us today to learn more about Genicular Artery Embolization (GAE). Our specialists will review your medical history, discuss your symptoms, and determine if GAE is the right solution for you.

Call Us: 415-221-7056
Location: 1 Daniel Burnham Court, Ste 205C, San Francisco, CA 94109
Request an Appointment: Click Here


Frequently Asked Questions (FAQs)

1. Is Genicular Artery Embolization covered by insurance?
Coverage varies by provider and plan. Many insurers cover GAE when it’s deemed medically necessary. Contact your insurance company or our office for assistance with prior authorization.

2. What are the success rates for GAE?
Clinical studies demonstrate a high success rate in reducing pain within the first month, with many patients experiencing relief lasting up to two years. The procedure has a technical success rate exceeding 99%.

3. How long does the pain relief last?
Most patients experience significant improvement for up to two years. Results may vary depending on the individual’s condition.

4. Are there risks or side effects?
GAE is safe, with minor side effects like temporary bruising, mild soreness, or skin discoloration. Serious complications are rare but will be discussed during your consultation.

5. Can I have GAE if I’ve already had knee surgery?
Yes, GAE can benefit patients who have had prior knee surgeries or are looking for non-surgical alternatives.

6. Am I a candidate for GAE?
GAE is recommended for patients who:

  • Are between 40-80 years old

  • Experience chronic knee pain from osteoarthritis that affects daily activities

  • Have tried conservative treatments (medications, physical therapy, or steroid injections) without success

  • Prefer to avoid or delay total knee replacement surgery

If you’re unsure whether GAE is right for you, schedule a consultation with our specialists.

7. What is the recovery time for GAE?
Most patients walk out of the facility within a few hours after the procedure. Mild soreness or bruising at the catheter insertion site may occur, but most individuals return to normal activities within a few days.

8. How is GAE different from a knee replacement?
GAE is a minimally invasive, non-surgical procedure that preserves your natural knee joint. Unlike knee replacement, there is no hospital stay, no large incisions, and no extensive recovery time.

9. Can GAE be repeated if my pain comes back?
Yes, in some cases, GAE can be repeated if knee pain returns over time. Our team can evaluate your condition and determine if a second procedure is appropriate.

10. Will GAE affect my ability to have a knee replacement in the future?
No, GAE does not alter the knee joint structure. If you decide to have a knee replacement later on, you will still be eligible.