Genicular Artery Embolization (GAE) for Chronic Knee Pain

If you're suffering from chronic knee pain due to osteoarthritis and want a non-surgical solution, Genicular Artery Embolization (GAE) may be right for you. This minimally invasive knee procedure offers long-lasting relief for those who haven't found success with physical therapy, injections, or medications.

What is GAE for Knee Pain?

Genicular Artery Embolization (GAE) is a minimally invasive outpatient procedure used to treat chronic knee pain caused by osteoarthritis. This innovative technique targets the small arteries around the knee (called genicular arteries) that supply blood to inflamed joint tissue. By reducing abnormal blood flow, GAE decreases inflammation and helps relieve pain—without the need for surgery.

This minimally invasive knee procedure is ideal for patients seeking long-term relief from chronic knee pain due to osteoarthritis—especially those hoping to avoid or delay knee replacement surgery.

The procedure is performed by a vascular surgeon using advanced imaging guidance. A small catheter is inserted through a tiny incision in the upper thigh (usually near the groin), allowing precise delivery of treatment directly to the arteries causing the problem. There are no stitches, and most patients walk out the same day.

Who is a Candidate for the GAE Procedure?

You may be a good candidate for Genicular Artery Embolization (GAE) if you:

• Are between the ages of 40 and 80

• Experience chronic knee pain from osteoarthritis

• Have not found relief with physical therapy, anti-inflammatory medications, or steroid injections

• Want to avoid or delay knee replacement surgery

• Are not a surgical candidate due to other health concerns

• Prefer a non-surgical, outpatient procedure with minimal recovery time

To find out if GAE is right for you, start by taking our short WOMAC Survey. A score above 25 may indicate that you’re a strong candidate. Afterward, schedule a consultation to review your results and discuss your treatment options with our team.

What to Expect During the GAE Procedure:

Genicular Artery Embolization (GAE) is performed in our Accredited Ambulatory Surgery Center (ASC) using advanced imaging guidance for maximum precision and comfort. Here’s what to expect:

Step-by-Step Overview

1. Preparation:
The procedure is done under local anesthesia with mild sedation. A small catheter is inserted into the femoral artery through a tiny puncture in the groin or upper thigh.

2. Targeting the Pain-Related Arteries:
With the help of real-time X-ray imaging (fluoroscopy), the physician guides the catheter to the genicular arteries that supply blood to inflamed tissue in the knee.

3. Embolization Process:
Once the target vessels are identified, microscopic particles are injected to reduce abnormal blood flow—relieving inflammation and pain.

4. Completion & Recovery:
The catheter is removed, and the puncture site is covered with a small bandage—no stitches are needed. Most patients walk out of the ASC within a few hours and resume normal activities within 1–2 days.

How Long Does Genicular Artery Embolization Last?

Many patients experience noticeable pain relief within days to weeks after the procedure, with continued improvement over several months. Clinical studies show that the effects of GAE for knee pain can last up to two years or more, especially in patients with moderate osteoarthritis.

While GAE does not reverse joint damage, it can provide long-term symptom relief, helping patients delay or avoid knee replacement surgery and reduce reliance on medications.

Key Benefits of GAE:

• Minimally Invasive: No incisions, stitches, or general anesthesia—just a small puncture and quick recovery.

• Outpatient Procedure: Performed in our Medicare-approved Ambulatory Surgical Center, allowing you to go home the same day.

• Fast Recovery: Most patients walk out within a few hours and return to normal activities in 1–2 days.

• Proven Results: Clinical studies show lasting pain relief—often up to two years or more.

• Reduced Reliance on Medications: Many patients need fewer or no pain medications after GAE.

• Non-Surgical Alternative to Knee Replacement: GAE provides effective relief without the risks, recovery, or downtime of major surgery.

Why Choose SFVVI?

At San Francisco Vein & Vascular Institute (SFVVI), we perform GAE in our Medicare-approved Ambulatory Surgical Center (ASC)—providing hospital-level safety in a comfortable outpatient setting.

What Sets Us Apart:

• Expertise: Led by Dr. Daniel Nathanson, Chief of Vascular Surgery at CPMC, one of the most experienced vascular surgeons in the region.

• Ambulatory Surgical Center Safety: Our facility meets strict national standards for safe, minimally invasive care.

• Advanced Technology: We use the latest imaging and embolization techniques for precise results.

• Personalized Care: From consultation to recovery, every treatment is tailored to your needs.

• Fast Recovery: As an outpatient procedure, most patients return home the same day and recover quickly—no hospital stay required.

Schedule a Consultation:

If you’re suffering from chronic knee pain due to osteoarthritis and want to explore a non-surgical alternative to knee replacement, contact us today to learn more about Genicular Artery Embolization (GAE). Our specialists will review your medical history, evaluate your symptoms, and determine if GAE for knee pain is the right solution for you.

Call Us: 415-221-7056
Location: 1 Daniel Burnham Court, Ste 205C, San Francisco, CA 94109
Schedule a Consultation

Frequently Asked Questions (FAQs)

1. Is Genicular Artery Embolization covered by insurance?
Coverage varies by provider and plan. Many insurers cover GAE when it’s deemed medically necessary. Contact your insurance company or our office for assistance with prior authorization.

2. What are the success rates for GAE?
Clinical studies demonstrate a high success rate in reducing pain within the first month, with many patients experiencing relief lasting up to two years. The procedure has a technical success rate exceeding 99%.

3. How long does the pain relief last?
Most patients experience significant improvement for up to two years. Results may vary depending on the individual’s condition.

4. Are there risks or side effects?
GAE is safe, with minor side effects like temporary bruising, mild soreness, or skin discoloration. Serious complications are rare but will be discussed during your consultation.

5. Can I have GAE if I’ve already had knee surgery?
Yes, GAE can benefit patients who have had prior knee surgeries or are looking for non-surgical alternatives.

6. Am I a candidate for GAE?
GAE is recommended for patients who:

• Are between 40-80 years old

• Experience chronic knee pain from osteoarthritis that affects daily activities

• Have tried conservative treatments (medications, physical therapy, or steroid injections) without success

• Prefer to avoid or delay total knee replacement surgery

If you’re unsure whether GAE is right for you, schedule a consultation with our specialists.

7. What is the recovery time for GAE?
Most patients walk out of the facility within a few hours after the procedure. Mild soreness or bruising at the catheter insertion site may occur, but most individuals return to normal activities within a few days.

8. How is GAE different from a knee replacement?
GAE is a minimally invasive, non-surgical procedure that preserves your natural knee joint. Unlike knee replacement, there is no hospital stay, no large incisions, and no extensive recovery time.

9. Can GAE be repeated if my pain comes back?
Yes, in some cases, GAE can be repeated if knee pain returns over time. Our team can evaluate your condition and determine if a second procedure is appropriate.

10. Will GAE affect my ability to have a knee replacement in the future?
No, GAE does not alter the knee joint structure. If you decide to have a knee replacement later on, you will still be eligible.